After their triumph over Riot, Eddie Brock and his alien parasite have agreed on a few rules of conduct. While Venom would rather eat bad guys all the time, Eddie is now desperate to relaunch his career as a journalist. Then serial killer Cletus Kasady arrives just in time to talk to Eddie about his victims. When Kasady transforms into the brutal Carnage during his execution and wreaks havoc everywhere, Venom must intervene.